HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: ANTR1 (Q9H6X2)
Anthrax toxin receptor 1 (Tumor endothelial marker 8)
Gene: ANTXR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 564
+	Hs
		564686 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		1330918 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		925617 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		951342 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		900907 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		545620 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		436510 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		892598 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Hs
		1183554 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		ANTR1_HUMAN (1-505): 0: 625: 100.00
+	Dr
		60120 RHOAB_DANRE (5-191): 7.17e-81: 240: 52.94		A4QP34_DANRE (20-489): 0: 535: 53.49
+	Hs
		564464 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880220 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880211 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880208 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880212 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880209 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		545290 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		436228 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83
+	Hs
		880207 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		ITA1_HUMAN (34-326): 1.84e-62: 224: 14.83