HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: RHG35 (Q9NRY4)
Rho GTPase-activating protein 35 (Glucocorticoid receptor DNA-binding factor 1) (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A)
Gene: ARHGAP35

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 9535855, 21311754
Identification Methods pull down, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~Ras, Ras~RhoGAP
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0032956 - regulation of actin cytoskeleton organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 1499
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024