HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: KC1G3 (Q9Y6M4)
Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1)
Gene: CSNK1G3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 447
+	Hs
		564761 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		925773 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		951505 RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		822374 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		KC1D_HUMAN (36-435): 1.44e-134: 395: 46.29
+	Hs
		901107 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		545731 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		436599 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		564425 RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94		AKT2_HUMAN (1-386): 6.22e-125: 373: 18.37
+	Hs
		892707 RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		821977 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KC1A_HUMAN (28-364): 3.67e-130: 381: 50.59
+	Hs
		1183632 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		KC1G3_HUMAN (1-447): 2.1e-138: 406: 100.00
+	Hs
		943160 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		KC1G2_HUMAN (5-447): 1.96e-125: 371: 75.23
+	Hs
		568794 RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		681775 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		AKT1_HUMAN (4-386): 2.58e-122: 366: 19.74
+	Hs
		568619 RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		568605 CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		568611 RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		545209 RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75		KAPCB_HUMAN (2-367): 3.04e-122: 361: 20.43
+	Hs
		436148 RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95
+	Hs
		568715 RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82		KAPCA_HUMAN (6-370): 6.92e-123: 363: 19.95