HitPredict

Interactor 1: DEST (P60981)
Destrin (Actin-depolymerizing factor) (ADF)
Gene: DSTN

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.934

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, unassigned1304, 31515488
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Cofilin_ADF
Common GO terms GO:0005737 - cytoplasm
GO:0048870 - cell motility
GO:0070062 - extracellular exosome
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 165
Hs

1 375
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Last updated: 15 Jul 2024