Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A
Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.913 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16902405, 26824392, 29125462, 21378754 |
| Identification Methods | pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, fluorescence polarization spectroscopy, x-ray crystallography, molecular sieving, two hybrid, enzyme linked immunosorbent assay |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ras~RhoGAP |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030670 - phagocytic vesicle membrane GO:0031267 - small GTPase binding GO:0060271 - cilium assembly |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
