HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26553929
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006904 - vesicle docking involved in exocytosis GO:0030670 - phagocytic vesicle membrane GO:0032588 - trans-Golgi network membrane and 1 others more... GO:0055038 - recycling endosome membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 100
+	Hs
		1079324 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		918878 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		1079428 RAB1B_HUMAN (1-204): 7.39e-87: 256: 51.96		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		926211 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		1079958 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		261649 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		914092 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		850554 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		913996 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Sc
		350845 YPT1_YEAST (1-204): 6.16e-81: 241: 49.03		SEC22_YEAST (1-97): 1.07e-21: 86.2: 18.56
+	Hs
		914322 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		263215 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		87580 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		C9JXZ5_HUMAN (29-81): 1.25e-16: 69.7: 37.74