HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: RIPL2 (Q969X0)
RILP-like protein 2 (Rab-interacting lysosomal protein-like 2) (p40phox-binding protein)
Gene: RILPL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.825

Property	Details
Experiments	29125462, 32017888
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	RILP~Ras
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005929 - cilium GO:0031267 - small GTPase binding GO:0036064 - ciliary basal body and 1 others more... GO:0060271 - cilium assembly
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 211
+	Hs
		895533 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		RIPL2_HUMAN (25-211): 4.46e-105: 303: 100.00
+	Mm
		877201 RAB8A_MOUSE (1-207): 1.2e-85: 253: 97.10		RIPL2_MOUSE (28-211): 4.9e-95: 276: 76.63
+	Hs
		895497 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		RIPL1_HUMAN (75-164): 3.4e-31: 119: 44.33
+	Hs
		894744 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		RIPL1_HUMAN (75-164): 3.4e-31: 119: 44.33
+	Mm
		877204 RAB8A_MOUSE (1-207): 1.2e-85: 253: 97.10		RIPL1_MOUSE (75-164): 6.09e-30: 115: 43.00
+	Hs
		914109 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		RIPL1_HUMAN (75-164): 3.4e-31: 119: 44.33