HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: TBC17 (Q9HA65)
TBC1 domain family member 17
Gene: TBC1D17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	22854040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH_RBD~Ras, RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0006914 - autophagy
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 648
+	Hs
		918951 RAB1A_HUMAN (1-204): 1.23e-87: 258: 54.41		TBC17_HUMAN (1-648): 0: 583: 100.00
+	Hs
		894778 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC15_HUMAN (5-639): 0: 539: 46.19
+	Os
		1130874 Q7XHP7_ORYSJ (4-204): 3.33e-96: 280: 61.39		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Os
		772871 RIC2_ORYSJ (4-205): 1.14e-80: 241: 41.06		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Os
		1130875 Q84TA8_ORYSJ (4-204): 1.28e-80: 240: 60.89		Q5SMT0_ORYSJ (2-600): 8.61e-132: 404: 28.29
+	Hs
		914465 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBD2B_HUMAN (1-644): 2.21e-103: 338: 15.53
+	Hs
		894747 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC9B_HUMAN (136-646): 3.23e-88: 301: 15.37
+	Hs
		894727 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		TBC8B_HUMAN (136-646): 4.89e-82: 282: 16.07
+	Hs
		895536 RAB10_HUMAN (3-181): 4.07e-93: 272: 75.98		EVI5L_HUMAN (205-640): 1.76e-76: 262: 14.71
+	Hs
		234378 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		EVI5_HUMAN (279-615): 9.14e-79: 268: 16.62
+	Hs
		1079972 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		TBC14_HUMAN (214-599): 8.67e-79: 266: 16.96
+	Hs
		1079952 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		EVI5L_HUMAN (205-640): 1.76e-76: 262: 14.71
+	Hs
		321281 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBCD8_HUMAN (137-647): 1.16e-80: 278: 13.60
+	Hs
		234370 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		EVI5_HUMAN (279-615): 9.14e-79: 268: 16.62
+	Hs
		914423 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBC14_HUMAN (214-599): 8.67e-79: 266: 16.96
+	Hs
		914391 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TB22B_HUMAN (193-582): 7.25e-80: 263: 18.90
+	Hs
		914275 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		EVI5L_HUMAN (205-640): 1.76e-76: 262: 14.71
+	Hs
		233036 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		TBC12_HUMAN (207-582): 1.53e-76: 261: 18.44
+	Sc
		350927 YPT1_YEAST (1-204): 6.16e-81: 241: 49.03		GYP1_YEAST (264-519): 7.47e-66: 229: 21.31