HitPredict

Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: MYO5B (Q9ULV0)
Unconventional myosin-Vb
Gene: MYO5B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	26553929, 17507647
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	DIL~Ras
Common GO terms	GO:0031267 - small GTPase binding GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 1848
+	Hs
		1079976 RB11B_HUMAN (4-204): 1.1e-88: 261: 41.63		MYO5B_HUMAN (1-1848): 0: 1243: 100.00
+	Hs
		914453 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		MYO5B_HUMAN (1-1848): 0: 1243: 100.00
+	Rn
		914521 RB11A_RAT (4-204): 5.02e-81: 242: 41.06		MYO5B_RAT (1-1848): 0: 1202: 89.74
+	Hs
		914486 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		MYO5A_HUMAN (1-1848): 0: 1157: 61.96
+	Ce
		1088854 RAB10_CAEEL (1-204): 1.51e-86: 255: 68.29		Q17383_CAEEL (9-1848): 0: 914: 33.81
+	Hs
		894813 RAB8A_HUMAN (1-207): 1.67e-86: 255: 100.00		MYO5C_HUMAN (848-1848): 5.22e-71: 266: 28.40
+	Hs
		914383 RB11A_HUMAN (4-204): 5.02e-81: 242: 41.06		MYO5C_HUMAN (848-1848): 5.22e-71: 266: 28.40
+	At
		1338479 RABD1_ARATH (1-203): 2.3e-83: 247: 53.70		MYO6_ARATH (1216-1835): 5.22e-45: 181: 15.40
+	Zm
		14343 B4FNJ6_MAIZE (5-175): 1.01e-84: 251: 70.93		A0A1D6G388_MAIZE (1315-1583): 3.34e-09: 64.3: 12.59