HitPredict

Interactor 1: SRP54 (P61011)
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein)
Gene: SRP54

Interactor 2: SRP68 (Q9UHB9)
Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)
Gene: SRP68

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 35271311, 37071682, 23221635
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	SRP54~SRP68
Common GO terms	GO:0003723 - RNA binding GO:0005783 - endoplasmic reticulum GO:0005786 - signal recognition particle, endoplasmic reticulum targeting GO:0005829 - cytosol GO:0006614 - SRP-dependent cotranslational protein targeting to membrane and 2 others more... GO:0008312 - 7S RNA binding GO:0030942 - endoplasmic reticulum signal peptide binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	504
Hs

1	627

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024