Interactor 1: SRP54 (P61011)
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein)
Gene: SRP54

Interactor 2: SRPRB (Q9Y5M8)
Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1)
Gene: SRPRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SRP54~SRPRB
Common GO terms GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0045047 - protein targeting to ER
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 504
Hs

1 271
+ Sc
+ Dm
+ Hs
+ Hs
+ Sc
+ Hs
+ Tt

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Last updated: 15 Jul 2024