HitPredict

Interactor 1: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Interactor 2: TBC25 (Q3MII6)
TBC1 domain family member 25
Gene: TBC1D25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.80	0.755

Property	Details
Experiments	32296183, 16923123, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 212 Hs			1 688
+	Os
		1130874 Q7XHP7_ORYSJ (3-212): 9.35e-96: 279: 46.45		Q5SMT0_ORYSJ (85-434): 5.7e-89: 294: 29.30
+	Os
		1130875 Q84TA8_ORYSJ (3-212): 2.56e-95: 278: 44.08		Q5SMT0_ORYSJ (85-434): 5.7e-89: 294: 29.30
+	Os
		1130873 Q6YY17_ORYSJ (1-188): 4.07e-82: 244: 83.51		Q5SMT0_ORYSJ (85-434): 5.7e-89: 294: 29.30
+	Os
		772871 RIC2_ORYSJ (2-212): 9.06e-82: 244: 45.97		Q5SMT0_ORYSJ (85-434): 5.7e-89: 294: 29.30
+	Hs
		914391 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TB22B_HUMAN (14-515): 7.13e-86: 280: 16.32
+	Dm
		1197045 Q86BK8_DROME (3-205): 7.85e-85: 252: 60.10		Q9VPL5_DROME (112-475): 1.79e-78: 266: 27.08
+	Hs
		895106 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		TB10B_HUMAN (114-617): 1.78e-72: 252: 15.89
+	Hs
		914176 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TBCD1_HUMAN (78-609): 9.38e-74: 260: 16.42
+	Dm
		185563 RAB2_DROME (1-212): 1.05e-86: 256: 88.73		Q9VKV6_DROME (144-437): 1.92e-69: 242: 30.10
+	Hs
		918951 RAB1A_HUMAN (3-212): 3.93e-84: 249: 45.24		TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22
+	Dm
		1197047 Q86BK8_DROME (3-205): 7.85e-85: 252: 60.10		EVI5_DROME (113-434): 6.61e-69: 242: 19.51
+	Hs
		233036 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TBC12_HUMAN (119-454): 3.1e-70: 245: 14.69
+	Hs
		914423 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TBC14_HUMAN (108-467): 5.14e-71: 245: 15.26
+	Hs
		895137 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		TBCD9_HUMAN (152-445): 1.51e-64: 234: 17.79
+	Hs
		1079972 RB11B_HUMAN (3-212): 1.54e-82: 246: 47.62		TBC14_HUMAN (108-467): 5.14e-71: 245: 15.26
+	Hs
		321281 RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67		TBCD8_HUMAN (153-446): 2.61e-64: 233: 18.12
+	Hs
		195595 RAB2A_HUMAN (1-212): 1.36e-87: 258: 100.00		SGSM2_HUMAN (288-433): 3.21e-57: 211: 37.42
+	Hs
		195603 RAB2B_HUMAN (1-212): 1.08e-86: 256: 82.87		SGSM2_HUMAN (288-433): 3.21e-57: 211: 37.42
+	Hs
		233033 RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53		TBC12_HUMAN (119-454): 3.1e-70: 245: 14.69
+	Hs
		321271 RAB4A_HUMAN (3-188): 6.91e-72: 219: 57.53		TBCD8_HUMAN (153-446): 2.61e-64: 233: 18.12