HitPredict

Interactor 1: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Interactor 2: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	16923123
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH_RBD~Ras, RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 691
+	Hs
		592392 RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		844641 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		918951 RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Hs
		895381 RAB5B_HUMAN (1-215): 4.67e-90: 265: 100.00		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Hs
		592503 RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Hs
		844743 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Os
		772871 RIC2_ORYSJ (7-214): 1.65e-86: 256: 37.04		Q5SMT0_ORYSJ (11-641): 2.37e-147: 446: 30.74
+	Dm
		1358729 RAB5_DROME (3-213): 2.42e-97: 283: 72.51		Q9VPL5_DROME (8-629): 2.78e-132: 408: 31.81
+	Hs
		592528 RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86		TB22B_HUMAN (157-625): 1.72e-89: 290: 18.68
+	Hs
		914391 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		TB22B_HUMAN (157-625): 1.72e-89: 290: 18.68
+	Sc
		350927 YPT1_YEAST (14-213): 2.68e-91: 268: 41.46		GYP1_YEAST (285-557): 1.13e-79: 268: 22.85
+	Hs
		914275 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		EVI5L_HUMAN (233-676): 1.48e-82: 279: 14.00
+	Hs
		914423 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		TBC14_HUMAN (207-642): 1.52e-83: 279: 14.55
+	Hs
		233036 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		TBC12_HUMAN (208-642): 9.47e-82: 277: 14.55
+	Hs
		321281 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		TBCD8_HUMAN (173-660): 1.44e-79: 276: 13.21
+	Hs
		895374 RAB5B_HUMAN (1-215): 4.67e-90: 265: 100.00		SGSM3_HUMAN (249-645): 6.76e-76: 260: 16.34
+	Hs
		914176 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		TBCD1_HUMAN (198-649): 1.54e-76: 268: 17.92
+	Hs
		592434 RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86		SGSM3_HUMAN (249-645): 6.76e-76: 260: 16.34
+	Hs
		844684 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		SGSM3_HUMAN (249-645): 6.76e-76: 260: 16.34
+	Hs
		234370 RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61		EVI5_HUMAN (272-636): 2.43e-75: 260: 16.17