HitPredict

Interactor 1: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Interactor 2: PRAF1 (Q9UI14)
Prenylated Rab acceptor protein 1 (PRA1 family protein 1)
Gene: RABAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 185
+	Hs
		918963 RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Rn
		192720 RAB1A_RAT (10-213): 8.59e-91: 266: 39.51		PRAF1_RAT (1-185): 2.6e-66: 202: 95.14
+	Hs
		1328155 RAB1B_HUMAN (13-213): 4.44e-89: 262: 39.30		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Hs
		592561 RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Hs
		844785 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	At
		1338115 RABD1_ARATH (16-213): 6.5e-91: 267: 40.00		PR1F4_ARATH (17-182): 3.68e-52: 166: 18.68
+	At
		285946 RAE1C_ARATH (16-213): 2.09e-85: 253: 36.28		PR1B4_ARATH (27-181): 6.01e-54: 172: 24.36
+	At
		1340495 RABD1_ARATH (16-213): 6.5e-91: 267: 40.00		PR1B6_ARATH (33-184): 5.4e-47: 154: 26.14
+	At
		1352357 RABD1_ARATH (16-213): 6.5e-91: 267: 40.00		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	At
		656921 RAE1C_ARATH (16-213): 2.09e-85: 253: 36.28		PR1F3_ARATH (17-182): 6.85e-48: 156: 18.07
+	At
		189209 RAE1A_ARATH (16-213): 9.41e-86: 254: 37.75		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	At
		656922 RAE1C_ARATH (16-213): 2.09e-85: 253: 36.28		PR1B6_ARATH (33-184): 5.4e-47: 154: 26.14
+	At
		681157 RAF2A_ARATH (22-186): 1.28e-76: 230: 70.30		PR1B5_ARATH (21-181): 3.41e-52: 168: 22.22
+	Hs
		277670 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		PRAF3_HUMAN (39-185): 1.57e-39: 134: 21.85
+	Sc
		350904 YPT1_YEAST (14-213): 2.68e-91: 268: 41.46		PRA1_YEAST (16-179): 9.48e-35: 122: 25.30
+	At
		681159 RAF2A_ARATH (22-186): 1.28e-76: 230: 70.30		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	Hs
		242240 RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13
+	Hs
		242233 RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13
+	Sc
		731190 VPS21_YEAST (16-188): 9.25e-64: 198: 59.55		PRA1_YEAST (16-179): 9.48e-35: 122: 25.30
+	Sc
		731227 YPT52_YEAST (20-214): 1.51e-53: 173: 43.97		PRA1_YEAST (16-179): 9.48e-35: 122: 25.30