HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: SYTL3 (Q4VX76)
Synaptotagmin-like protein 3 (Exophilin-6)
Gene: SYTL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11773082
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0070382 - exocytic vesicle
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 610
+	Hs
		1273004 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		SYTL4_HUMAN (1-609): 3.82e-137: 416: 30.79
+	Hs
		894790 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		SYTL4_HUMAN (1-609): 3.82e-137: 416: 30.79
+	Mm
		877205 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		SYTL4_MOUSE (1-609): 1.04e-135: 413: 28.59
+	Hs
		1273014 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RP3A_HUMAN (8-610): 3.07e-125: 386: 18.54
+	Mm
		812770 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RP3A_MOUSE (8-610): 7.65e-133: 405: 18.33
+	Hs
		894828 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RP3A_HUMAN (8-610): 3.07e-125: 386: 18.54
+	Hs
		914274 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		SYTL4_HUMAN (1-609): 3.82e-137: 416: 30.79
+	Hs
		894765 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		SYTL1_HUMAN (4-609): 4.52e-88: 286: 23.29
+	Hs
		914240 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		SYTL5_HUMAN (2-377): 4.42e-43: 166: 20.85
+	Hs
		1134943 RAB1B_HUMAN (3-200): 5.28e-86: 253: 50.50		SYT6_HUMAN (123-435): 4.35e-20: 95.9: 13.17
+	Hs
		129082 RAB1A_HUMAN (1-200): 4.66e-87: 256: 50.24		SYT5_HUMAN (301-408): 1.42e-19: 92.9: 24.07
+	Mm
		895586 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RIMS1_MOUSE (456-599): 3.86e-15: 81.2: 17.81
+	Hs
		48320 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		ESYT2_HUMAN (308-433): 5.52e-12: 70.9: 31.78