HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: MICA3 (Q7RTP6)
[F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3)
Gene: MICAL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26824392
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ras~bMERB_dom
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 2002
+	Hs
		1186079 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		894754 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		914166 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		MICA3_HUMAN (1-2002): 0: 1314: 100.00
+	Hs
		894779 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Hs
		895525 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Hs
		918915 RAB1A_HUMAN (1-200): 4.66e-87: 256: 50.24		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Hs
		1255762 RAB1B_HUMAN (3-200): 5.28e-86: 253: 50.50		MICA1_HUMAN (8-1107): 0: 950: 37.63
+	Mm
		292526 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		ACTN3_MOUSE (434-1057): 1.37e-102: 354: 14.60
+	Hs
		914014 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		SPTB2_HUMAN (433-1059): 2.31e-85: 314: 16.56
+	Mm
		1112011 RAB13_MOUSE (1-200): 4.12e-82: 243: 62.00		MILK2_MOUSE (518-1453): 5.89e-67: 249: 17.00
+	Hs
		894773 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		914223 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		EHBP1_HUMAN (520-762): 2.11e-37: 156: 22.53
+	Hs
		1232324 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		1222038 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		MILK2_HUMAN (1084-1644): 1.03e-13: 79: 17.65
+	Hs
		894767 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		894763 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		MILK2_HUMAN (1084-1644): 1.03e-13: 79: 17.65
+	Hs
		895513 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		845869 RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		914208 RB11A_HUMAN (3-200): 6.11e-83: 246: 40.19		MILK1_HUMAN (715-885): 2.96e-16: 87.2: 21.14
+	Hs
		845867 RAB13_HUMAN (4-174): 1.52e-83: 247: 69.59		MILK2_HUMAN (1084-1644): 1.03e-13: 79: 17.65