HitPredict

Interactor 1: RAB10 (P61026)
Ras-related protein Rab-10 (EC 3.6.5.2)
Gene: RAB10

Interactor 2: RB33B (Q9H082)
Ras-related protein Rab-33B
Gene: RAB33B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0000139 - Golgi membrane GO:0005525 - GTP binding GO:0005768 - endosome GO:0005794 - Golgi apparatus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 229
+	Mm
		877189 RAB8B_MOUSE (1-198): 3.07e-100: 290: 70.20		RAB8A_MOUSE (26-226): 2.83e-87: 258: 38.54
+	Hs
		895217 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB2A_HUMAN (29-220): 1.13e-86: 257: 39.18
+	Hs
		1273009 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB1B_HUMAN (26-229): 8.1e-86: 254: 38.35
+	Hs
		894715 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB1A_HUMAN (23-229): 3.09e-87: 258: 37.62
+	Hs
		894787 RAB8B_HUMAN (1-198): 2.21e-100: 290: 70.20		RAB8A_HUMAN (26-226): 4.97e-80: 240: 37.56
+	Zm
		73944 B4FAE1_MAIZE (3-200): 8.03e-89: 260: 53.23		B4FAE1_MAIZE (26-229): 6.15e-89: 262: 36.72
+	Hs
		894709 RAB8A_HUMAN (1-199): 1.02e-96: 281: 67.32		RAB10_HUMAN (26-229): 1.81e-80: 240: 35.78
+	Hs
		895549 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1B_HUMAN (26-229): 8.1e-86: 254: 38.35
+	Mm
		895587 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Mm
		877188 RAB8A_MOUSE (4-181): 5.12e-93: 271: 75.98		RAB10_MOUSE (26-229): 1.81e-80: 240: 35.78
+	Mm
		919000 RAB1A_MOUSE (1-200): 4.66e-87: 256: 50.24		RAB1B_MOUSE (26-229): 1.17e-85: 254: 38.35
+	Hs
		895532 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB1C_HUMAN (26-229): 1.02e-82: 246: 37.86
+	Sc
		350828 YPT1_YEAST (3-200): 7.2e-90: 263: 50.24		YPT1_YEAST (26-229): 3.07e-80: 240: 35.07
+	Mm
		895589 RAB10_MOUSE (1-200): 3.02e-89: 262: 100.00		RAB13_MOUSE (26-229): 1.49e-80: 241: 36.77
+	Hs
		59815 RAB10_HUMAN (1-200): 3.02e-89: 262: 100.00		RAB19_HUMAN (33-221): 2.74e-46: 154: 41.89