HitPredict

Interactor 1: UB2D3 (P61077)
Ubiquitin-conjugating enzyme E2 D3 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D3) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D3) (Ubiquitin carrier protein D3) (Ubiquitin-conjugating enzyme E2(17)KB 3) (Ubiquitin-conjugating enzyme E2-17 kDa 3) (Ubiquitin-protein ligase D3)
Gene: UBE2D3

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 17719635, 19549727
Identification Methods affinity chromatography technology, two hybrid, two hybrid array
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-C3HC4_2
Common GO terms GO:0000209 - protein polyubiquitination
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 147
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024