HitPredict

Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 27591266, 21946088, 19245792, 27348078, 28581483, 28475037, 37028429, 21247897, 18826954, 17914462
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction, neddylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin_Nedd8~UQ_con
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 183
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024