HitPredict

Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Interactor 2: KLDC2 (Q9Y2U9)
Kelch domain-containing protein 2 (Hepatocellular carcinoma-associated antigen 33) (Host cell factor homolog LCP) (Host cell factor-like protein 1) (HCLP-1)
Gene: KLHDC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28581483
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 406
+	Hs
		299511 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLH18_HUMAN (87-405): 5.72e-60: 206: 15.85
+	Hs
		896269 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLH20_HUMAN (165-406): 2.16e-53: 189: 13.17
+	Hs
		895941 UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51		KLHL3_HUMAN (165-400): 3.41e-45: 166: 14.41
+	Hs
		896128 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLD10_HUMAN (139-399): 2.36e-38: 145: 17.84
+	Hs
		896288 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		NS1BP_HUMAN (122-404): 4.29e-37: 144: 11.01
+	Hs
		849329 UB2D1_HUMAN (30-173): 2.47e-75: 224: 30.14		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Zm
		25805 B6SZE0_MAIZE (30-174): 1.1e-75: 225: 31.29		A0A1D6IWK2_MAIZE (8-255): 1.73e-26: 113: 18.46
+	Hs
		828997 UBE2A_HUMAN (26-172): 2.67e-69: 208: 28.19		KEAP1_HUMAN (226-406): 5.71e-30: 123: 15.76
+	Hs
		896200 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLDC3_HUMAN (5-195): 2.91e-29: 119: 16.58
+	Hs
		896117 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLH12_HUMAN (6-156): 1.27e-25: 110: 16.56
+	Hs
		849470 UB2D1_HUMAN (30-173): 2.47e-75: 224: 30.14		KLHL9_HUMAN (265-402): 2.48e-13: 73.6: 15.07
+	Hs
		849471 UB2D1_HUMAN (30-173): 2.47e-75: 224: 30.14		KLH13_HUMAN (280-402): 3.05e-13: 73.2: 13.74
+	Hs
		896241 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLHL9_HUMAN (265-402): 2.48e-13: 73.6: 15.07
+	Hs
		896243 UBC12_HUMAN (1-183): 5.92e-69: 209: 100.00		KLH13_HUMAN (280-402): 3.05e-13: 73.2: 13.74