HitPredict

Interactor 1: UBC12 (P61081)
NEDD8-conjugating enzyme Ubc12 (EC 2.3.2.34) (NEDD8 carrier protein) (Ubiquitin-conjugating enzyme E2 M)
Gene: UBE2M

Interactor 2: FBX7 (Q9Y3I1)
F-box only protein 7
Gene: FBXO7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	27503909, 28581483
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 522
+	Hs
		849495 UB2D1_HUMAN (30-173): 2.47e-75: 224: 30.14		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		919914 UB2D2_HUMAN (30-173): 3.54e-75: 223: 32.19		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		895963 UB2D3_HUMAN (30-173): 1.29e-73: 219: 31.51		FBX7_HUMAN (1-522): 0: 1102: 100.00
+	Hs
		851911 UB2E1_HUMAN (5-173): 1.45e-72: 218: 28.07		FBX7_HUMAN (1-522): 0: 1102: 100.00