HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: LRSM1 (Q6UWE0)
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)
Gene: LRSAM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 723
+	Hs
		1165227 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		849345 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		919756 UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		895817 UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		851826 UB2E1_HUMAN (3-153): 1.87e-66: 203: 39.74		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		72141 B3KSH4_HUMAN (104-200): 1.63e-61: 187: 100.00		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Hs
		896468 UBE2N_HUMAN (27-153): 1.06e-37: 129: 51.97		LRSM1_HUMAN (1-723): 4.35e-103: 333: 100.00
+	Zm
		21257 A0A1D6LKH6_MAIZE (1-151): 6.08e-68: 207: 32.45		A0A1D6HSI7_MAIZE (3-306): 3.53e-52: 197: 15.81