HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: PJA1 (Q8NG27)
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING finger protein 70) (RING-type E3 ubiquitin transferase Praja-1)
Gene: PJA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21461837
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 643
+	Hs
		196282 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94
+	Hs
		196372 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		PJA2_HUMAN (1-642): 1.14e-129: 399: 44.94
+	Hs
		896385 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		RNF12_HUMAN (1-641): 4.33e-52: 191: 12.42
+	Hs
		896325 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		RN111_HUMAN (33-643): 6.96e-48: 183: 13.06
+	Hs
		849491 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RNF6_HUMAN (1-640): 5.26e-52: 192: 14.82
+	Hs
		1346940 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RNF12_HUMAN (1-641): 4.33e-52: 191: 12.42
+	Hs
		849459 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RNF12_HUMAN (1-641): 4.33e-52: 191: 12.42
+	Hs
		1169203 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RN111_HUMAN (33-643): 6.96e-48: 183: 13.06
+	Hs
		849348 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RN111_HUMAN (33-643): 6.96e-48: 183: 13.06
+	Hs
		282581 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RNF8_HUMAN (383-639): 1.07e-34: 139: 16.85
+	Hs
		1377467 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RN115_HUMAN (432-639): 6.28e-33: 130: 21.88
+	Hs
		849497 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RN115_HUMAN (432-639): 6.28e-33: 130: 21.88
+	Hs
		1242076 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		ZNRF1_HUMAN (383-633): 8.23e-33: 128: 14.68
+	Hs
		849373 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		ZNRF1_HUMAN (383-633): 8.23e-33: 128: 14.68
+	Hs
		1356934 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RN150_HUMAN (523-643): 1.36e-29: 123: 23.39
+	Hs
		849485 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RN150_HUMAN (523-643): 1.36e-29: 123: 23.39
+	Hs
		1313520 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RN126_HUMAN (545-639): 9.16e-30: 121: 40.00
+	Hs
		849428 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RN126_HUMAN (545-639): 9.16e-30: 121: 40.00
+	Hs
		1349753 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		RN181_HUMAN (566-640): 6.22e-29: 114: 38.67
+	Hs
		849467 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RN181_HUMAN (566-640): 6.22e-29: 114: 38.67