HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: TRI63 (Q969Q1)
E3 ubiquitin-protein ligase TRIM63 (EC 2.3.2.27) (Iris RING finger protein) (Muscle-specific RING finger protein 1) (MuRF-1) (MuRF1) (RING finger protein 28) (RING-type E3 ubiquitin transferase TRIM63) (Striated muscle RING zinc finger protein) (Tripartite motif-containing protein 63)
Gene: TRIM63

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	17426036
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 353
+	Hs
		1151762 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		Q6GX22_HUMAN (14-337): 5.23e-87: 277: 23.68
+	Hs
		896381 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI39_HUMAN (14-352): 5.49e-70: 229: 16.80
+	Hs
		536773 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI27_HUMAN (8-353): 1.89e-68: 225: 17.49
+	Hs
		896348 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI43_HUMAN (10-351): 1.53e-67: 220: 13.74
+	Hs
		175659 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65
+	Hs
		896371 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRIM2_HUMAN (10-330): 1.64e-63: 216: 19.52
+	Hs
		1317493 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI54_HUMAN (7-326): 7.72e-74: 234: 61.37
+	Hs
		896370 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRIM5_HUMAN (10-346): 1.16e-64: 214: 17.49
+	Hs
		537142 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI27_HUMAN (8-353): 1.89e-68: 225: 17.49
+	Hs
		896394 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRIM1_HUMAN (14-345): 3.61e-59: 205: 22.00
+	Hs
		1285831 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI43_HUMAN (10-351): 1.53e-67: 220: 13.74
+	Hs
		175730 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI18_HUMAN (43-337): 4.87e-65: 219: 23.65
+	Hs
		896369 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI31_HUMAN (8-301): 3.28e-59: 198: 21.77
+	Hs
		1318358 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRIM8_HUMAN (15-330): 6.11e-65: 216: 20.87
+	Hs
		135045 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI38_HUMAN (8-352): 1.89e-63: 210: 17.68
+	Hs
		262201 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRIM3_HUMAN (9-346): 3.33e-61: 210: 17.53
+	Hs
		1313765 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI62_HUMAN (16-286): 7.47e-58: 196: 22.71
+	Hs
		896330 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI50_HUMAN (14-250): 3.59e-14: 75.1: 25.00
+	Hs
		896326 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI67_HUMAN (75-147): 2.92e-12: 69.8: 29.49
+	Hs
		1204911 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI50_HUMAN (14-250): 3.59e-14: 75.1: 25.00