HitPredict

Interactor 1: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Interactor 2: TRI34 (Q9BYJ4)
E3 ubiquitin-protein ligase TRIM34 (EC 2.3.2.27) (Interferon-responsive finger protein 1) (RING finger protein 21)
Gene: TRIM34

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 488
+	Hs
		584907 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		RO52_HUMAN (1-487): 4.51e-144: 423: 41.80
+	Hs
		896381 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI39_HUMAN (6-487): 1.28e-135: 403: 30.48
+	Hs
		896370 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRIM5_HUMAN (1-488): 1.64e-134: 399: 55.75
+	Hs
		536773 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI27_HUMAN (1-487): 3.11e-130: 389: 30.95
+	Hs
		1336390 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI39_HUMAN (6-487): 1.28e-135: 403: 30.48
+	Hs
		1318719 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRIM5_HUMAN (1-488): 1.64e-134: 399: 55.75
+	Hs
		536760 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		TRI27_HUMAN (1-487): 3.11e-130: 389: 30.95
+	Hs
		537142 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI27_HUMAN (1-487): 3.11e-130: 389: 30.95
+	Hs
		135012 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		TRI38_HUMAN (1-487): 1.47e-117: 355: 32.60
+	Hs
		135045 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI38_HUMAN (1-487): 1.47e-117: 355: 32.60
+	Hs
		896348 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI43_HUMAN (1-475): 9.75e-110: 334: 27.67
+	Hs
		1285831 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI43_HUMAN (1-475): 9.75e-110: 334: 27.67
+	Hs
		1377469 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI17_HUMAN (2-479): 3.2e-109: 334: 28.40
+	Hs
		896330 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI50_HUMAN (1-476): 9.37e-101: 312: 24.08
+	Hs
		1354526 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI10_HUMAN (1-485): 1.08e-106: 327: 25.25
+	Hs
		896398 UBE2K_HUMAN (1-200): 1.35e-82: 245: 100.00		TRI35_HUMAN (3-486): 9.32e-98: 305: 21.49
+	Hs
		1204911 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI50_HUMAN (1-476): 9.37e-101: 312: 24.08
+	Hs
		849314 UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74		TRI26_HUMAN (1-485): 5.96e-100: 312: 25.51
+	Hs
		1357712 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI35_HUMAN (3-486): 9.32e-98: 305: 21.49
+	Hs
		1313765 UB2D4_HUMAN (4-154): 1.49e-75: 225: 41.72		TRI62_HUMAN (8-483): 4.23e-96: 300: 24.65