HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: UB2V1 (Q13404)
Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A)
Gene: UBE2V1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 18029035, 18082144, 27173435, 32659264, 11057907, 20613989, 16215985, 18678647, 17709375, 25548215, 29069608, 29662619, 29537486, 33961781, 16307917, 16129784, 15147900, 22367539, 21460221, 26101372 and 1 others

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Identification Methods pull down, affinity chromatography technology, biochemical, two hybrid, molecular sieving, enzymatic study, ubiquitinase assay, anti tag coimmunoprecipitation, mass spectrometry studies of complexes
Interaction Type direct interaction, physical association, association, deubiquitination reaction, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~UQ_con
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 10 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 152
Hs

1 147
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Last updated: 15 Jul 2024