HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: SH3R1 (Q7Z6J0)
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING finger protein 142) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)
Gene: SH3RF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	17420289, 19393081
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 888
+	Hs
		849352 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		SH3R1_HUMAN (1-888): 1.17e-136: 431: 100.00
+	Hs
		895828 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		SH3R1_HUMAN (1-888): 1.17e-136: 431: 100.00
+	Hs
		277030 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		277046 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		277041 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		STAM2_HUMAN (436-755): 1.43e-22: 104: 13.81
+	Hs
		896502 UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00		SH3R2_HUMAN (762-888): 9.07e-12: 71: 22.84
+	Hs
		829090 UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46		CD2AP_HUMAN (764-888): 1.62e-12: 73.3: 30.47