HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: SH3R2 (Q8TEC5)
E3 ubiquitin-protein ligase SH3RF2 (EC 2.3.2.27) (Heart protein phosphatase 1-binding protein) (HEPP1) (POSH-eliminating RING protein) (Protein phosphatase 1 regulatory subunit 39) (RING finger protein 158) (RING-type E3 ubiquitin transferase SH3RF2) (SH3 domain-containing RING finger protein 2)
Gene: SH3RF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 729
+	Hs
		849352 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		SH3R1_HUMAN (1-729): 3.75e-52: 196: 26.51
+	Hs
		895828 UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89		SH3R1_HUMAN (1-729): 3.75e-52: 196: 26.51
+	Hs
		896478 UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00		SH3R1_HUMAN (1-729): 3.75e-52: 196: 26.51
+	Hs
		829090 UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46		CD2AP_HUMAN (103-227): 2.25e-15: 82: 16.80