HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: TRI34 (Q9BYJ4)
E3 ubiquitin-protein ligase TRIM34 (EC 2.3.2.27) (Interferon-responsive finger protein 1) (RING finger protein 21)
Gene: TRIM34

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	35065966
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Hs			1 488
+	Hs
		849366 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI22_HUMAN (1-488): 1.46e-145: 427: 60.44
+	Hs
		584907 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		RO52_HUMAN (1-487): 4.51e-144: 423: 41.80
+	Hs
		1336390 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI39_HUMAN (6-487): 1.28e-135: 403: 30.48
+	Hs
		1318719 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRIM5_HUMAN (1-488): 1.64e-134: 399: 55.75
+	Hs
		537142 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI27_HUMAN (1-487): 3.11e-130: 389: 30.95
+	Hs
		536760 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI27_HUMAN (1-487): 3.11e-130: 389: 30.95
+	Hs
		849406 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI11_HUMAN (2-486): 1.1e-128: 383: 33.67
+	Hs
		135045 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI38_HUMAN (1-487): 1.47e-117: 355: 32.60
+	Hs
		135012 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI38_HUMAN (1-487): 1.47e-117: 355: 32.60
+	Hs
		1285831 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI43_HUMAN (1-475): 9.75e-110: 334: 27.67
+	Hs
		1377469 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI17_HUMAN (2-479): 3.2e-109: 334: 28.40
+	Hs
		849399 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI43_HUMAN (1-475): 9.75e-110: 334: 27.67
+	Hs
		1354526 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI10_HUMAN (1-485): 1.08e-106: 327: 25.25
+	Hs
		849358 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI69_HUMAN (5-487): 8.82e-105: 323: 25.25
+	Hs
		1204911 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI50_HUMAN (1-476): 9.37e-101: 312: 24.08
+	Hs
		849314 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI26_HUMAN (1-485): 5.96e-100: 312: 25.51
+	Hs
		849360 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI50_HUMAN (1-476): 9.37e-101: 312: 24.08
+	Hs
		1357712 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI35_HUMAN (3-486): 9.32e-98: 305: 21.49
+	Hs
		1313765 UB2D4_HUMAN (4-149): 5.39e-81: 236: 45.89		TRI62_HUMAN (8-483): 4.23e-96: 300: 24.65
+	Hs
		849384 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		TRI41_HUMAN (1-43): 2.71e-11: 68: 41.86