HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RN167 (Q9H6Y7)
E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167)
Gene: RNF167

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 33650289, 19690564
Identification Methods pull down, two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0070534 - protein K63-linked ubiquitination
GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 152
Hs

1 350
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024