HitPredict

Interactor 1: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Interactor 2: RC3H2 (Q9HBD1)
Roquin-2 (EC 2.3.2.27) (Membrane-associated nucleic acid-binding protein) (RING finger and CCCH-type zinc finger domain-containing protein 2) (RING finger protein 164) (RING-type E3 ubiquitin transferase Roquin-2)
Gene: RC3H2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	26489670, 19549727
Identification Methods	pull down, two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_5
Common GO terms	GO:0003723 - RNA binding GO:0050852 - T cell receptor signaling pathway
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 152 Hs			1 1191
+	Hs
		919868 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1297369 UB2E2_HUMAN (1-149): 1.52e-75: 225: 44.97		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		1282349 UB2E3_HUMAN (1-149): 3.17e-75: 224: 44.97		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		927778 UBE2B_HUMAN (1-146): 2.71e-69: 207: 39.46		RC3H2_HUMAN (1-1191): 0: 1105: 100.00
+	Hs
		919745 UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		896459 UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		829015 UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		927756 UBE2B_HUMAN (1-146): 2.71e-69: 207: 39.46		RC3H1_HUMAN (1-1108): 0: 788: 49.30
+	Hs
		849390 UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21		CBP_HUMAN (556-893): 1.74e-09: 64.6: 9.77