HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005911 - cell-cell junction GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 217
+	Hs
		891671 ACTB_HUMAN (1-414): 0: 539: 35.66		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924453 ACTG_HUMAN (1-414): 0: 538: 35.42		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924456 ACTC_HUMAN (3-414): 0: 527: 35.59		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924454 ACTH_HUMAN (3-414): 0: 524: 35.59		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		337422 ACTS_HUMAN (3-414): 0: 528: 35.59		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		454818 ACTB_HUMAN (1-414): 0: 539: 35.66		FGR_HUMAN (120-215): 6.83e-13: 68.8: 22.45
+	Hs
		442804 ACTB_HUMAN (1-414): 0: 539: 35.66		HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39
+	Hs
		548675 ACTA_HUMAN (3-414): 0: 526: 35.59		VAV_HUMAN (2-60): 8.95e-15: 74.6: 42.37
+	Hs
		522893 ACTS_HUMAN (3-414): 0: 528: 35.59		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58