HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 535
+	Hs
		896807 ARP3_HUMAN (1-418): 0: 588: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		1306714 ARP3B_HUMAN (1-418): 0: 580: 90.67		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		943520 ARP3B_HUMAN (1-418): 0: 580: 90.67		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		826595 ARP3_HUMAN (1-418): 0: 588: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826924 ARP3B_HUMAN (1-418): 0: 580: 90.67		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		891991 ACTB_HUMAN (1-414): 0: 539: 35.66		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		573196 ARP3_HUMAN (1-418): 0: 588: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821146 ARP3_HUMAN (1-418): 0: 588: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		929984 ACTG_HUMAN (1-414): 0: 538: 35.42		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		891685 ACTB_HUMAN (1-414): 0: 539: 35.66		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		929820 ACTG_HUMAN (1-414): 0: 538: 35.42		TCPB_HUMAN (1-535): 0: 586: 100.00
+	Hs
		573511 ARP3B_HUMAN (1-418): 0: 580: 90.67		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		826593 ACTB_HUMAN (1-414): 0: 539: 35.66		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Hs
		826609 ACTG_HUMAN (1-414): 0: 538: 35.42		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Sc
		760666 ACT_YEAST (1-414): 0: 528: 34.94		TCPB_YEAST (9-532): 0: 566: 65.71
+	Hs
		573194 ACTB_HUMAN (1-414): 0: 539: 35.66		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821144 ACTB_HUMAN (1-414): 0: 539: 35.66		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Hs
		573210 ACTG_HUMAN (1-414): 0: 538: 35.42		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		821160 ACTG_HUMAN (1-414): 0: 538: 35.42		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Sc
		760791 ACT_YEAST (1-414): 0: 528: 34.94		TCPG_YEAST (5-528): 0: 537: 28.33