HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 418 Hs			1 1025
+	Hs
		891851 ACTB_HUMAN (1-414): 0: 539: 35.66		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		896788 ARP3_HUMAN (1-418): 0: 588: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		896760 ARP3_HUMAN (1-418): 0: 588: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		892089 ACTB_HUMAN (1-414): 0: 539: 35.66		SWP70_HUMAN (370-824): 7.27e-58: 212: 19.22
+	Hs
		929935 ACTG_HUMAN (1-414): 0: 538: 35.42		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		148601 ARP3_HUMAN (1-418): 0: 588: 100.00		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		929898 ACTG_HUMAN (1-414): 0: 538: 35.42		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		724742 ARP3_HUMAN (1-418): 0: 588: 100.00		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		148662 ACTC_HUMAN (3-414): 0: 527: 35.59		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		522576 ARP3B_HUMAN (1-418): 0: 580: 90.67		MYH1_HUMAN (122-873): 2.75e-15: 83.2: 8.13
+	Hs
		728459 ARP3_HUMAN (1-418): 0: 588: 100.00		MYH11_HUMAN (124-786): 1.25e-12: 74.7: 11.57
+	Mm
		892205 ACTB_MOUSE (1-414): 0: 539: 35.66		MYH9_MOUSE (542-1025): 4.68e-18: 92.5: 8.68
+	Rn
		892228 ACTB_RAT (1-414): 0: 539: 35.66		MYH9_RAT (566-1025): 4.61e-18: 92.5: 9.81
+	Hs
		724738 ACTB_HUMAN (1-414): 0: 539: 35.66		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724762 ACTG_HUMAN (1-414): 0: 538: 35.42		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Rn
		892236 ACTB_RAT (1-414): 0: 539: 35.66		MYH10_RAT (534-1014): 1.07e-15: 84.8: 11.32
+	Hs
		724767 ACTS_HUMAN (3-414): 0: 528: 35.59		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		724766 ACTC_HUMAN (3-414): 0: 527: 35.59		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		929869 ACTG_HUMAN (1-414): 0: 538: 35.42		PLEC_HUMAN (499-978): 3.1e-11: 70.1: 14.96
+	Hs
		255307 ACTB_HUMAN (1-414): 0: 539: 35.66		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56