HitPredict

Interactor 1: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Interactor 2: WASF3 (Q9UPY6)
Actin-binding protein WASF3 (Protein WAVE-3) (Verprolin homology domain-containing protein 3) (Wiskott-Aldrich syndrome protein family member 3) (WASP family protein member 3)
Gene: WASF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10381382
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Actin~WH2
Common GO terms	GO:0030027 - lamellipodium GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 502
+	Hs
		896793 ARP3_HUMAN (1-418): 0: 588: 100.00		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		896858 ARP3_HUMAN (1-418): 0: 588: 100.00		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		930055 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF3_HUMAN (1-502): 1.19e-73: 243: 100.00
+	Hs
		929950 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF1_HUMAN (1-500): 3.42e-59: 206: 43.57
+	Hs
		892150 ACTB_HUMAN (1-414): 0: 539: 35.66		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Rn
		892225 ACTB_RAT (1-414): 0: 539: 35.66		WASF1_RAT (1-500): 1.87e-56: 199: 43.04
+	Hs
		930077 ACTG_HUMAN (1-414): 0: 538: 35.42		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	Hs
		932482 ACTC_HUMAN (3-414): 0: 527: 35.59		WASF2_HUMAN (1-484): 2.01e-57: 200: 43.60
+	At
		1338960 ARP3_ARATH (6-417): 0: 523: 59.10		SCAR3_ARATH (1-162): 6.62e-47: 177: 21.69
+	Hs
		203220 ACTC_HUMAN (3-414): 0: 527: 35.59		SYNJ1_HUMAN (11-499): 4.06e-38: 151: 11.82
+	Hs
		891942 ACTB_HUMAN (1-414): 0: 539: 35.66		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Hs
		915464 ACTA_HUMAN (3-414): 0: 526: 35.59		CBP_HUMAN (153-498): 1.18e-22: 104: 13.84
+	Hs
		554290 ACTA_HUMAN (3-414): 0: 526: 35.59		MUC1_HUMAN (77-452): 1.55e-13: 75.5: 11.00