HitPredict

Interactor 1: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Interactor 2: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton GO:0051015 - actin filament binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 394 Hs			1 649
+	Hs
		891799 ACTB_HUMAN (1-388): 0: 574: 46.65		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		929879 ACTG_HUMAN (3-388): 0: 573: 46.37		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		932187 ACTC_HUMAN (2-388): 0: 569: 46.51		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		915391 ACTA_HUMAN (3-388): 0: 567: 45.86		DREB_HUMAN (1-649): 5.59e-95: 307: 100.00
+	Hs
		892099 ACTB_HUMAN (1-388): 0: 574: 46.65		DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98
+	Hs
		932439 ACTC_HUMAN (2-388): 0: 569: 46.51		DBNL_HUMAN (3-464): 1.68e-73: 244: 29.98
+	Ce
		501469 ACT2_CAEEL (1-388): 0: 578: 46.65		Q9XUT0_CAEEL (4-564): 1.01e-44: 171: 16.98
+	Hs
		891932 ACTB_HUMAN (1-388): 0: 574: 46.65		CTTB2_HUMAN (131-644): 3.31e-33: 139: 14.55
+	Sc
		551386 ACT_YEAST (1-387): 0: 565: 45.74		ABP1_YEAST (4-508): 1.78e-30: 128: 13.51
+	Dm
		950123 ACT6_DROME (1-388): 0: 571: 46.13		TITIN_DROME (173-542): 1.72e-27: 121: 13.80
+	Sc
		551351 ARP2_YEAST (9-390): 0: 549: 67.89		ABP1_YEAST (4-508): 1.78e-30: 128: 13.51
+	Dm
		54871 ACT6_DROME (1-388): 0: 571: 46.13		A1ZA72_DROME (119-642): 1.06e-09: 64.1: 10.13
+	Hs
		203220 ACTC_HUMAN (2-388): 0: 569: 46.51		SYNJ1_HUMAN (103-518): 1.79e-09: 63.3: 9.35