Interactor 1: ACTZ (P61163)
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)
Gene: ACTR1A

Interactor 2: DCTN2 (Q13561)
Dynactin subunit 2 (50 kDa dynein-associated polypeptide) (Dynactin complex 50 kDa subunit) (DCTN-50) (p50 dynamitin)
Gene: DCTN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 27173435, 34079125, 33961781, 35235311, 26186194, 28514442, 35271311
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Dynamitin
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005869 - dynactin complex
GO:0070062 - extracellular exosome
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 376
Hs

1 401
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024