HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: DCA11 (Q8TEB1)
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)
Gene: DCAF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 19295130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 546
+	Hs
		121820 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00
+	Hs
		1024190 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00
+	Hs
		1255949 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		DCA11_HUMAN (18-546): 5.28e-125: 379: 100.00
+	Hs
		121725 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		WDR5_HUMAN (470-546): 1.74e-12: 70.6: 16.67
+	Hs
		121982 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		WDR5_HUMAN (470-546): 1.74e-12: 70.6: 16.67