HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	23441852
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 2442
+	Hs
		897234 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998723 PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998633 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		999036 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		897279 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		1024193 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36
+	Hs
		1262810 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		PHIP_HUMAN (1045-1205): 3.22e-45: 183: 30.36