HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 30833792, 22268729
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 293
+	Hs
		1024224 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1311903 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		897290 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83
+	Hs
		1024203 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83
+	Hs
		1289617 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		FBX17_HUMAN (12-262): 4.9e-118: 342: 33.83