HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: KLHL8 (Q9P2G9)
Kelch-like protein 8
Gene: KLHL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 620
+	Hs
		897257 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH12_HUMAN (47-602): 0: 530: 37.75
+	Hs
		299512 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH18_HUMAN (35-600): 3.09e-179: 521: 34.63
+	Hs
		897262 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH10_HUMAN (55-601): 1.12e-169: 498: 29.33
+	Hs
		1024231 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLHL8_HUMAN (1-620): 0: 553: 100.00
+	Hs
		1024168 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH12_HUMAN (47-602): 0: 530: 37.75
+	Hs
		299514 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH18_HUMAN (35-600): 3.09e-179: 521: 34.63
+	Hs
		1120807 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH12_HUMAN (47-602): 0: 530: 37.75
+	Hs
		299532 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH18_HUMAN (35-600): 3.09e-179: 521: 34.63
+	Hs
		1024172 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH10_HUMAN (55-601): 1.12e-169: 498: 29.33
+	Hs
		1153792 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH10_HUMAN (55-601): 1.12e-169: 498: 29.33
+	Hs
		897322 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH13_HUMAN (414-620): 2.6e-49: 183: 26.51
+	Hs
		897264 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		KLH24_HUMAN (492-619): 8.17e-18: 89: 21.05
+	Hs
		1024232 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLHL9_HUMAN (414-620): 3.96e-50: 185: 26.98
+	Hs
		1024234 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH13_HUMAN (414-620): 2.6e-49: 183: 26.51
+	Hs
		1311911 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		KLH13_HUMAN (414-620): 2.6e-49: 183: 26.51
+	Hs
		1024173 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH24_HUMAN (492-619): 8.17e-18: 89: 21.05
+	Hs
		1024184 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		KLH36_HUMAN (508-618): 6.62e-16: 83.3: 24.17