HitPredict

Interactor 1: CSN2 (P61202)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: Cops2

Interactor 2: CSN8 (Q8VBV7)
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (JAB1-containing signalosome subunit 8)
Gene: Cops8

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24973710
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CSN8_PSD8_EIF3K~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005634 - nucleus GO:0008180 - COP9 signalosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 443 Mm			1 209
+	Hs
		897300 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		CSN8_HUMAN (1-209): 3.32e-112: 321: 95.22
+	Mm
		102352 G3UXW9_MOUSE (17-443): 1.81e-80: 259: 15.39		CSN8_MOUSE (1-209): 3.71e-113: 323: 100.00
+	Hs
		1024210 CSN1_HUMAN (17-443): 7.03e-80: 257: 15.02		CSN8_HUMAN (1-209): 3.32e-112: 321: 95.22
+	Mm
		1257402 CSN1_MOUSE (17-443): 1.68e-79: 255: 15.39		CSN8_MOUSE (1-209): 3.71e-113: 323: 100.00
+	Hs
		1305342 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		CSN8_HUMAN (1-209): 3.32e-112: 321: 95.22
+	At
		794512 CSN4_ARATH (73-439): 8.3e-58: 196: 15.21		CSN8_ARATH (10-209): 2.26e-75: 227: 32.84
+	At
		794509 CSN1_ARATH (231-442): 2.95e-44: 162: 21.15		CSN8_ARATH (10-209): 2.26e-75: 227: 32.84