HitPredict

Interactor 1: CSN2 (P61203)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: Cops2

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Rn			1 810
+	Hs
		475555 CSN2_HUMAN (1-443): 3.15e-127: 377: 100.00		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		121666 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475779 PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		121918 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476293 CSN4_HUMAN (54-440): 8.14e-74: 238: 16.25		UBC_HUMAN (1-533): 0: 662: 99.81
+	Sc
		477496 RPN6_YEAST (67-443): 8.69e-76: 245: 21.43		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	At
		1092149 PSD11_ARATH (42-443): 2.17e-80: 256: 22.98		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092027 PS12A_ARATH (43-440): 7.05e-75: 242: 10.14		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091832 PS12B_ARATH (43-440): 1.95e-73: 238: 10.60		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1091885 PSMD6_ARATH (79-440): 2.11e-72: 234: 15.32		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Mm
		476740 CSN2_MOUSE (1-443): 3.15e-127: 377: 100.00		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		121730 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		923997 PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		121987 PSD12_HUMAN (39-440): 8.69e-83: 263: 12.80		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476877 PSD11_MOUSE (35-442): 4.29e-89: 278: 22.67		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		476962 PSMD6_MOUSE (55-440): 9.34e-86: 269: 12.76		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		121663 PSD11_HUMAN (35-442): 5.44e-89: 278: 22.43		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Mm
		102344 G3UXW9_MOUSE (17-443): 1.81e-80: 259: 15.39		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Mm
		477004 PSD12_MOUSE (40-440): 3.38e-80: 256: 12.83		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397972 PSMD6_HUMAN (55-440): 4.29e-87: 272: 13.01		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69