HitPredict

Interactor 1: RPAB2 (P61218)
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15)
Gene: POLR2F

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.925

Property	Details
Experiments	26496610, 33961781, 35271311, 24981860, 33674783
Identification Methods	affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb2_7~RNA_pol_Rpb6
Common GO terms	GO:0001056 - RNA polymerase III activity GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 1133
+	Hs
		87262 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		C9J2Y9_HUMAN (14-1127): 0: 1476: 37.52
+	Hs
		676852 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		RPB2_HUMAN (14-1127): 0: 1475: 37.52
+	Sc
		593204 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPC2_YEAST (12-1130): 0: 1471: 62.84
+	Sp
		736922 RPAB2_SCHPO (1-124): 1.18e-45: 146: 51.75		RPB2_SCHPO (19-1131): 0: 1388: 34.93
+	Sc
		439968 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPB2_YEAST (13-1130): 0: 1382: 36.70
+	Pf
		1257370 RPO6_PYRFU (58-108): 4.79e-21: 81.4: 43.14		Q8U0M3_PYRFU (22-1130): 0: 1318: 36.92
+	Hs
		897631 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		RPA2_HUMAN (36-1128): 0: 1159: 29.59
+	Sc
		593202 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPA2_YEAST (12-1129): 0: 1047: 28.42