HitPredict

Interactor 1: RPAB2 (P61218)
DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15)
Gene: POLR2F

Interactor 2: RPA12 (Q9P1U0)
DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) (Zinc ribbon domain-containing protein 1)
Gene: POLR1H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0005654 - nucleoplasm GO:0005736 - RNA polymerase I complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 127 Hs			1 126
+	Hs
		738835 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		RPB9_HUMAN (11-124): 2.03e-35: 119: 16.95
+	Hs
		897668 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		RPC10_HUMAN (16-124): 3.48e-29: 103: 22.12
+	Sc
		593210 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPB9_YEAST (15-125): 6.62e-32: 110: 21.43
+	Hs
		612972 RPAB2_HUMAN (1-127): 9.52e-51: 158: 100.00		TCEA1_HUMAN (28-123): 2.77e-25: 98.7: 19.39
+	Sc
		593263 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPC10_YEAST (16-125): 7.49e-30: 105: 26.72
+	Sc
		593215 RPAB2_YEAST (2-126): 1.14e-46: 149: 49.65		RPA12_YEAST (12-126): 7.84e-27: 98.3: 33.87
+	Dm
		1097353 RPAB2_DROME (29-127): 3.3e-41: 134: 71.57		Q9VXS6_DROME (28-124): 6.97e-17: 73.6: 12.00