HitPredict

Interactor 1: RAP1B (P61224)
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)
Gene: RAP1B

Interactor 2: ZDH17 (Q8IUH5)
Palmitoyltransferase ZDHHC17 (EC 2.3.1.225) (Acyltransferase ZDHHC17) (EC 2.3.1.-) (DHHC domain-containing cysteine-rich protein 17) (DHHC17) (Huntingtin yeast partner H) (Huntingtin-interacting protein 14) (HIP-14) (Huntingtin-interacting protein 3) (HIP-3) (Huntingtin-interacting protein H) (Putative MAPK-activating protein PM11) (Putative NF-kappa-B-activating protein 205) (Zinc finger DHHC domain-containing protein 17)
Gene: ZDHHC17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.80	0.625

Property	Details
Experiments	24705354
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Hs			1 632
+	Hs
		925204 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		ANK2_HUMAN (2-451): 6.06e-82: 284: 17.14
+	Hs
		925238 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		ANK3_HUMAN (2-438): 1.56e-79: 277: 17.73
+	Hs
		349253 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		ANK2_HUMAN (2-451): 6.06e-82: 284: 17.14
+	Hs
		350083 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		ANK2_HUMAN (2-451): 6.06e-82: 284: 17.14
+	Hs
		350123 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		ANK3_HUMAN (2-438): 1.56e-79: 277: 17.73
+	Hs
		914450 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		925723 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		350674 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		KDIS_HUMAN (2-403): 1.47e-66: 239: 14.82
+	Hs
		350675 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		ANR50_HUMAN (71-327): 4.74e-53: 198: 23.89
+	Hs
		862018 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		DAPK1_HUMAN (127-398): 2.56e-34: 142: 17.15
+	Hs
		349212 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		DAPK1_HUMAN (127-398): 2.56e-34: 142: 17.15
+	Hs
		897946 RAP1B_HUMAN (1-184): 3.62e-74: 222: 100.00		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		918940 RAB1A_HUMAN (4-183): 4.68e-73: 220: 31.49		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		1318844 RAB1B_HUMAN (4-179): 4.82e-71: 215: 29.94		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		914339 RB11A_HUMAN (4-178): 2.05e-69: 211: 28.98		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		925592 RAC1_HUMAN (1-184): 1.05e-68: 209: 27.55		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		350317 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		ZDH17_HUMAN (2-147): 3.29e-28: 121: 16.22
+	Hs
		349624 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		350522 RASK_HUMAN (1-167): 6.26e-55: 174: 57.49		ZDHC5_HUMAN (370-594): 3.11e-18: 90.9: 29.79
+	Hs
		349748 RASH_HUMAN (1-167): 1.22e-55: 175: 57.49		ZDHC9_HUMAN (361-612): 1.42e-18: 89.7: 26.79