HitPredict

Interactor 1: RAP2B (P61225)
Ras-related protein Rap-2b (EC 3.6.5.2)
Gene: RAP2B

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 193
+	Hs
		901077 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		925756 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436584 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		545712 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		892695 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		916092 RAP2C_HUMAN (1-182): 1.79e-102: 294: 86.26		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		893856 RAP2B_HUMAN (1-183): 8.63e-88: 256: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		900355 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		918847 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436244 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		436498 RAB1B_HUMAN (4-179): 6.08e-75: 224: 33.90		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		918849 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		893872 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545307 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		894409 RAB1B_HUMAN (4-179): 6.08e-75: 224: 33.90		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		845846 RAB13_HUMAN (4-167): 9.1e-78: 232: 32.73		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		915583 RAP1A_HUMAN (1-183): 3.49e-78: 232: 60.87		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		892305 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		915582 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120378 RAB1A_HUMAN (4-182): 1.23e-75: 226: 34.44		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98