Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: MAD1 (Q05195)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: MXD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 26186194, 28514442, 26264872, 8425218, 17418410, 10229200, 29028833, 27705803, 12391307, 9528857, 33961781, 12553908, 16140957, 16596619, 8224841, 9886493
Identification Methods affinity chromatography technology, pull down, two hybrid, x-ray crystallography, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 160
Hs

1 221
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Gg
+ Rn
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ At
+ Hs

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Last updated: 15 Jul 2024