HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27705803, 24981860, 29028833
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 406
+	Hs
		545963 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		346606 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Hs
		379317 MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67		RING1_HUMAN (1-406): 2.01e-114: 342: 100.00
+	Mm
		659355 MAX_MOUSE (1-160): 4.6e-32: 113: 99.38		RING2_MOUSE (8-406): 2.94e-100: 303: 54.25
+	Hs
		898178 MAX_HUMAN (1-160): 2.05e-31: 112: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		347679 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		379766 MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		379067 MYCN_HUMAN (7-101): 2.1e-21: 91.1: 33.67		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Hs
		347835 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		TRIM6_HUMAN (39-392): 1.17e-47: 171: 12.53
+	Hs
		898188 MAX_HUMAN (1-160): 2.05e-31: 112: 100.00		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		584889 SRBP1_HUMAN (9-149): 2.92e-25: 102: 20.00		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Mm
		659354 MAX_MOUSE (1-160): 4.6e-32: 113: 99.38		PCGF6_MOUSE (31-157): 7.63e-39: 144: 23.08
+	Hs
		345897 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		RO52_HUMAN (33-392): 4.67e-43: 158: 13.14
+	Hs
		347818 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		749531 USF2_HUMAN (16-115): 1.18e-24: 99.1: 29.91		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63
+	Hs
		347755 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		346112 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63