HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	29028833, 25609649, 11509179, 33961781, 20946988
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 160 Hs			1 3159
+	Hs
		546032 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		229350 MAX_HUMAN (1-160): 2.05e-31: 112: 100.00		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		658645 MAX_HUMAN (1-160): 2.05e-31: 112: 100.00		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		229308 USF1_HUMAN (10-115): 4.62e-23: 94.1: 30.97		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		229271 MYC_HUMAN (14-105): 1.81e-21: 91.5: 34.74		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		607786 USF1_HUMAN (10-115): 4.62e-23: 94.1: 30.97		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Dm
		631342 MYC_DROME (22-118): 9.41e-23: 95.3: 26.53		BRM_DROME (1527-2267): 3.24e-149: 512: 14.69
+	Hs
		607839 USF1_HUMAN (10-115): 4.62e-23: 94.1: 30.97		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	At
		1107221 MYC2_ARATH (2-123): 1.53e-25: 103: 19.70		BRM_ARATH (1848-2491): 4.41e-71: 269: 18.39
+	At
		188528 BH003_ARATH (8-123): 1.38e-21: 91.8: 18.80		BRM_ARATH (1848-2491): 4.41e-71: 269: 18.39
+	Mm
		659350 MAX_MOUSE (1-160): 4.6e-32: 113: 99.38		EP400_MOUSE (2511-3159): 1.94e-10: 69.5: 10.79
+	Hs
		738947 SRBP1_HUMAN (9-149): 2.92e-25: 102: 20.00		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Mm
		1111973 SRBP1_MOUSE (9-134): 2.94e-25: 102: 19.38		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		738948 SRBP1_HUMAN (9-149): 2.92e-25: 102: 20.00		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		545949 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		545950 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Mm
		348440 MYC_MOUSE (19-105): 1.04e-21: 91.9: 37.50		EP400_MOUSE (2511-3159): 1.94e-10: 69.5: 10.79
+	Mm
		524521 MYOG_MOUSE (11-118): 1.06e-23: 94.1: 18.52		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		546075 MYOG_HUMAN (11-118): 4.7e-23: 92.6: 19.44		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Mm
		348422 MYC_MOUSE (19-105): 1.04e-21: 91.9: 37.50		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57